Embryologi

Noninferiority, randomized, controlled trial comparing embryo development using media developed for sequential or undisturbed culture in a time-lapse setup. Hardarson T, Bungum M, Conaghan J, Meintjes M, Chantilis SJ, Molnar L, Gunnarsson K, Wikland M. Fertil Steril. 2015 Dec;104(6):1452-9.e1-4.

The Alpha Consensus Meeting on the professional status of the clinical embryologist: proceedings of an expert meeting. Alpha Scientists in Reproductive Medicine. Reprod Biomed Online. 2015 May;30(5):451-61.

Choosing the best embryo by time lapse versus standard morphology.Kirkegaard K, Ahlström A, Ingerslev HJ, Hardarson T. Fertil Steril. 2015 Feb;103(2):323-32.

No evidence that embryo selection by near-infrared spectroscopy in addition to morphology is able to improve live birth rates: results from an individual patient data meta-analysis. Vergouw CG, Heymans MW, Hardarson T, Sfontouris IA, Economou KA, Ahlström A, Rogberg L, Lainas TG, Sakkas D, Kieslinger DC, Kostelijk EH, Hompes PG, Schats R, Lambalk CB. Hum Reprod. 2014 Mar;29(3):455-61.

Proteomic analysis of human blastocoel fluid and blastocyst cells. Jensen PL, Beck HC, Petersen J, Hreinsson J, Wånggren K, Laursen SB, Sørensen PD, Christensen ST, Andersen CY. Stem Cells Dev. 2013 Apr 1;22(7):1126-35.

Prediction of live birth in frozen-thawed single blastocyst transfer cycles by pre-freeze and post-thaw morphology. Ahlström A, Westin C, Wikland M, Hardarson T. Hum Reprod. 2013 May;28(5):1199-209.

Glycoprotein 130 promotes human blastocyst development in vitro.Hambiliki F, Hanrieder J, Bergquist J, Hreinsson J, Stavreus-Evers A, Wånggren K. Fertil Steril. 2013 May;99(6):1592-9.

The blastocyst. Hardarson T, Van Landuyt L, Jones G. Hum Reprod. 2012 Aug;27 Suppl 1:i72-91.

Non-invasive metabolomic profiling of Day 2 and 5 embryo culture medium: a prospective randomized trial. Hardarson T, Ahlström A, Rogberg L, Botros L, Hillensjö T, Westlander G, Sakkas D, Wikland M. Hum Reprod. 2012 Jan;27(1):89-96.

Receiver operating characteristic (ROC) analysis of day 5 morphology grading and metabolomic Viability Score on predicting implantation outcome. Seli E, Bruce C, Botros L, Henson M, Roos P, Judge K, Hardarson T, Ahlström A, Harrison P, Henman M, Go K, Acevedo N, Siques J, Tucker M, Sakkas D. J Assist Reprod Genet. 2011 Feb;28(2):137-44.

Trophectoderm morphology: an important parameter for predicting live birth after single blastocyst transfer.
A. Ahlström, C. Westin, E. Reismer, M. Wikland, and T. Hardarson
Human Reproduction, Vol.0, No.0 pp. 1–8, 2011

Non-invasive metabolomic profiling of Day 2 and 5 embryo culture media: a prospective randomized study.
Hardarson T, Ahlström A, Rogberg L, Botros L, Hillensjö T, Westlander G, Sakkas D, Wikland M
Human Reproduction 2011 accepted for publication.

Trophectoderm morphology: an important parameter for predicting live birth after single blastocyst transfer. Ahlström A, Westin C, Reismer E, Wikland M, Hardarson T. Hum Reprod. 2011 Dec;26(12):3289-96.

The Istanbul consensus workshop on embryo assessment: proceedings of an expert meeting. Alpha Scientists in Reproductive Medicine and ESHRE Special Interest Group of Embryology. Hum Reprod. 2011 Jun;26(6):1270-83.

Cross-validation and predictive value of near-infrared spectroscopy algorithms for day-5 blastocyst transfer. Ahlström A, Wikland M, Rogberg L, Barnett JS, Tucker M, Hardarson T. Reprod Biomed Online. 2011 May;22(5):477-84.

Low-oxygen compared with high-oxygen atmosphere in blastocyst culture, a prospective randomized study.
Waldenström U, Engström AB, Hellberg D, Nilsson S.
Fertil Steril. 2009 Jun; 91(6):2461-5.

Granulocyte-macrophage colony-stimulating factor alleviates adverse consequences of embryo culture on fetal growth trajectory and placental morphogenesis. Sjöblom C, Roberts CT, Wikland M, Robertson SA.
Endocrinology. 2005 May; 146(5):2142-53. Epub 2005 Feb 10.

Promising results with 306 single blastocyst transfers.
Nilsson S, Waldenström U, Engström AB, Hellberg D. Fertil Steril. 2005 Jun; 83(6):1849-51.

A randomized, double-blind, controlled trial of the effect of adding follicular fluid meiosis activating sterol in an ethanol formulation to donated human cumulus-enclosed oocytes before fertilization.
Loft A, Bergh C, Ziebe S, Lundin K, Andersen AN, Wikland M, Kim H, Arce JC. Fertil Steril. 2004 Jan; 81(1):42-50.

Granulocyte-macrophage colony-stimulating factor (GM-CSF) acts independently of the beta common subunit of the GM-CSF receptor to prevent inner cell mass apoptosis in human embryos.
Sjöblom C, Wikland M, Robertson SA. Biol Reprod. 2002 Dec; 67(6):1817-23.

Laser zona pellucida thinning–an alternative approach to assisted hatching.
Blake DA, Forsberg AS, Johansson BR, Wikland M. Hum Reprod. 2001 Sep; 16(9):1959-64.